Anavex Life Sciences Corp. has a productive drug discovery platform with a broad IP portfolio based on unique expertise of sigma receptors ligands. ANAVEX 2-73 has succesfully completed a Phase 1 single ascending dose clinical trial of ANAVEX 2-73, lead drug candidate for the treatment of Alzheimer’s Disease (AD). Several other new drug candidates with high affinity for sigma receptors are close to entering Phase 1 clinical trials. The synergetic effects of sigma receptors offer a new neuroprotective mechanism in AD and other Central Nervous System disorders such as epilepsy and depression. Anavex proprietary sigma ligands induce apoptosis in cancer cells in a selective way. Anavex oncology candidates show promising pro-apoptotic activity in several in vivo models of solid tumors.

According to 2011 Alzheimer’s Disease Facts and Figures, released by the Alzheimer’s Association, there are nearly 15 million Alzheimer’s and dementia caregivers in the United States. This new report shows that there are far more Alzheimer’s and dementia caregivers than previously believed – 37% more than reported last year. These individuals provided 17 billion hours of unpaid care valued at $202.6 billion. If Alzheimer’s and dementia caregivers were the only residents of a single state it would be the 5th largest state in the country. more