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In 2020, Alzheimer’s and other dementias cost the nation $305 billion. By 2050, these costs could rise as high as $1.1 trillion.[5] There are currently over 50 million people and Biology Volume 964 (2017) Sigma Receptors: Their Role in Disease and as Therapeutic Targets. [2] https /health/alzheimers ; https://www.alz.org/alzheimers-dementia/facts-figures . [6] Alzheimer’s Disease World Alzheimer Report 2019. https://www.alz.co.uk/research/WorldAlzheimerReport2019.pdf . [7] AARP.

In 2020, Alzheimer’s and other dementias cost the nation approximately $305 billion. By 2050, these costs could rise as high as $1.1 trillion.[6] There are currently over 50 million people and Biology Volume 964 (2017) Sigma Receptors: Their Role in Disease and as Therapeutic Targets. [4] https /health/alzheimers ; https://www.alz.org/alzheimers-dementia/facts-figures . [7] Alzheimer’s Disease World Alzheimer Report 2019. https://www.alz.co.uk/research/WorldAlzheimerReport2019.pdf . [8] AARP.

The current annual cost of dementia is estimated at $1 trillion, a figure set to double by 2030[2] and The full paper can be accessed online at: ( https://alz-journals.onlinelibrary.wiley.com/doi/full/10.1002 (Nasdaq: AVXL) is a publicly traded biopharmaceutical company dedicated to the development of differentiated Research & Business Development Toll-free: 1-844-689-3939 Email: info@anavex.com Investors & Media : Email: ir@anavex.com [1] www.apmiscience.com [2] https://www.alz.org/alzheimers-dementia/

program designed to facilitate and expedite the development and review of a new drug to address unmet medical of a serious and life-threatening condition for which it demonstrates the potential to address unmet medical the program is to get important new therapies to the patients earlier in order to address the unmet medical life-threatening conditions for which there is a demonstration of the potential to address an unmet medical and Biology Volume 964 (2017) Sigma Receptors: Their Role in Disease and as Therapeutic Targets. [2] http

Additional information is available on the conference web site at http://www.alz.org/icad/overview.asp The ANAVEX abstract can be viewed by visiting http://www.alz.org/icad/abstract.asp and doing a search Medications currently available to treat Alzheimer’s disease include acetylcholinesterase inhibitors Both types of medications only treat symptoms of the disease — they do not stop the onset and progression In conclusion, there are very real and unmet medical requirements for drug therapies to treat Alzheimer

Data from this study will be submitted later this year for presentation at a scientific medical meeting Mov Disord. 2018 May;33(5):771-782. doi: 10.1002/mds.27361 [7] https://www.anavex.com/wp-content/uploads Acta Neurol Scand 2010; 122:270–7 [9] https://www.anavex.com/anavex-life-sciences-reports-anavex2-73 / ; https://www.anavex.com/anavex-awarded-grant-from-the-michael-j-fox-foundation-for-parkinsons-research / [13] ClinicalTrials.gov Identifier: NCT03774459 [14] Source: https://www.alz.org/alzheimers-dementia

efficient way,” said Christopher U. “This is an exciting time for our Company given the properties of ANAVEX 2-73 and the vast unmet medical It is believed this advantage will allow the trial to more efficiently demonstrate the effects of the About Alzheimer’s Disease Today, Alzheimer’s disease remains the largest unmet medical need in neurology More than 25 million people are currently diagnosed with Alzheimer’s, with the associated cost of care

Strengthening Operational Efficiency and Execution towards Sustainable Accessibility for Diverse Populations Reinforcing the Company’s commitment to drive value-creation through operational efficiencies and innovation Lopez-Talavera was Assistant Professor at the University of Pittsburgh Medical Center and postdoctoral executive leadership positions in Clinical Development, Regulatory Affairs, Clinical Operations, and Medical (Nasdaq: AVXL) is a publicly traded biopharmaceutical company dedicated to the development of novel therapeutics

the data remains ongoing, and the Company plans to submit the data for publication in a peer-reviewed medical patients, caregivers, and healthcare systems worldwide,” said Edward R Hammond, MD, PhD, MPH, Chief Medical The estimated total healthcare costs for the treatment of Alzheimer's disease in 2020 were estimated Most of the direct costs of care for Alzheimer's disease are attributed to skilled nursing care, home and Biology Volume 964 (2017) Sigma Receptors: Their Role in Disease and as Therapeutic Targets. [5] https

In 2020, Alzheimer’s and other dementias cost the nation $305 billion. By 2050, these costs could rise as high as $1.1 trillion.[15] There are currently over 50 million people Alzheimer’s & Dementia 14, P1519–P1520. https://doi.org/10.1016/j.jalz.2018.07.027 . [5] Hampel H. et Biology Volume 964 (2017) Sigma Receptors: Their Role in Disease and as Therapeutic Targets. [15] https World Alzheimer Report 2019. https://www.alz.co.uk/research/WorldAlzheimerReport2019.pdf . [17] AARP.

“We are honored to support medical professionals and their patients seeking treatment for Alzheimer’s disease and who have very few medical options,” commented Christopher U Missling, PhD, President and The Special Access Scheme: Most therapeutic goods are required to undergo an evaluation for quality, projected in any of such statements due to various factors, including the risks set forth in the Company’s most : Email: ir@anavex.com [1] https://www.tga.gov.au/form/special-access-scheme

that the peer-reviewed scientific journal The Journal of Clinical Hypertension [1] has published a post-hoc was 69.5 years, 60% were male, mean body mass index was 26.5 kg/m2, and 50% were on antihypertensive medication There are properties of the medication that support a compelling mechanism for how it can lower high in healthy subjects, who demonstrated normal blood pressure levels at baseline, the results of the post-hoc of Pennsylvania, Philadelphia, PA, Michael Perlis, PhD is a consultant for Anavex Life Sciences [2] https