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What is Angelman syndrome?
Angelman syndrome is a genetic disorder. It causes delayed development, problems with speech and balance, intellectual disability, and sometimes, seizures. People with Angelman syndrome often smile and laugh frequently, and have happy, excitable personalities. Developmental delays, which begin between about 6 and 12 months of age, are usually the first signs of Angelman syndrome. Seizures may begin between the ages of 2 and 3 years old. People with Angelman syndrome tend to live close to a normal life span, but the disorder can't be cured. Current treatments focus on managing medical, sleep and developmental issues.
Signs & Symptoms
Common symptoms include intellectual disability, epilepsy, behavioral abnormalities (hyperactivity, anxiety, aggression, self-injurious behavior), and growth abnormalities.
Minimal Use of Speech
Neurodevelopmental delays are typically the first signs of Angelman syndrome.
Angelman syndrome affects males and females in equal numbers. The prevalence of Angelman syndrome is estimated to be approximately 1 in 12,000 - 20,000 people worldwide.