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View allAlzheimer's DiseaseAnavex2-73EventsNews ReleasesPDDPIPELINEPressRett Syndrome

Amyloid-beta junkies

February 26, 2000

Neuroactive neurosteroids as endogenous effectors for the sigma1 (σ1) receptor: Pharmacological evidence and therapeutic opportunities.

October 11, 1999

Intracellular σ1 receptor modulates phospholipase C and protein kinase C activities in the brainstem.

July 6, 1999

Sigma receptor photolabeling and sigma receptor-mediated modulation of potassium channels in tumor cells.

June 25, 1999

Olfactory bulbectomy increases prepro-enkephalin mRNA levels in the ventral striatum in rats.

June 11, 1999

A-current down-modulated by sigma receptor in frog pituitary melanotrope cells through a G-protein-dependent pathway.

April 11, 1999

Binding of dimemorfan to sigma-1 receptor and its anticonvulsant and locomotor effects in mice, compared with dextromethorphan and dextrorphan.

April 11, 1999

TAK-147, an acetylcholinesterase inhibitor, increases choline acetyltransferase activity in cultured rat septal cholinergic neurons.

January 22, 1999

Association between polymorphisms in the type 1 sigma receptor gene and schizophrenia.

November 20, 1998

Beneficial effects of acute and repeated administrations of sigma receptor agonists on behavioural despair in mice exposed to tail suspension.

November 11, 1998

Cloning and functional characterization of a sigma receptor from rat brain.

March 11, 1998

Sigma1 (σ1) receptor agonists and neurosteroids attenuate β25-35-amyloid peptide-induced amnesia in mice through a common mechanism.

March 11, 1998
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