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View allAlzheimer's DiseaseAnavex2-73EventsNews ReleasesPDDPIPELINEPressRett Syndrome

Sigma receptor type 1 gene expression variation in a group of Polish patients with Alzheimer’s disease and mild cognitive impairment.

January 10, 2007

Interactions between 3,4- methylenedioxymethamphetamine and sigma-1 receptors.

December 28, 2006

Sigma-1 receptor activation prevents intracellular calcium dysregulation in cortical neurons during in vitro ischemia.

December 11, 2006

The expression and functional characterization of sigma-1 receptors in breast cancer cell lines.

October 28, 2006

Intrathecal treatment with sigma-1 receptor antagonists reduces formalin-induced phosphorylation of NMDA receptor subunit 1 and the second phase of formalin test in mice.

June 11, 2006

Cocaine-induced HIV-1 expression in microglia involves sigma-1 receptors and transforming growth factor-beta1.

June 11, 2006

Sigma receptor activation reduces infarct size at 24 hours after permanent middle cerebral artery occlusion in rats.

May 11, 2006

A novel adamantane derivative attenuates retinal ischemia-reperfusion damage in the rat retina through sigma-1 receptors.

April 24, 2006

Chronic administration of dehydroepiandrosterone sulfate (DHEAS) primes for facilitated induction of long-term potentiation via sigma-1 receptor: Optical imaging study in rat hippocampal slices.

March 11, 2006

A variant of the sigma receptor type 1 gene is a protective factor for Alzheimer’s disease.

December 10, 2005

Inhibition of tumor cell proliferation by sigma ligands is associated with K+channel inhibition and p27kip accumulation.

December 11, 2004

Clinical trials with sigma ligands.

November 11, 2004
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