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View allAlzheimer's DiseaseAnavex2-73EventsNews ReleasesPIPELINEPressUncategorized

The expression and functional characterization of sigma-1 receptors in breast cancer cell lines.

Intrathecal treatment with sigma-1 receptor antagonists reduces formalin-induced phosphorylation of NMDA receptor subunit 1 and the second phase of formalin test in mice.

Cocaine-induced HIV-1 expression in microglia involves sigma-1 receptors and transforming growth factor-beta1.

Sigma receptor activation reduces infarct size at 24 hours after permanent middle cerebral artery occlusion in rats.

A novel adamantane derivative attenuates retinal ischemia-reperfusion damage in the rat retina through sigma-1 receptors.

Chronic administration of dehydroepiandrosterone sulfate (DHEAS) primes for facilitated induction of long-term potentiation via sigma-1 receptor: Optical imaging study in rat hippocampal slices.

Inhibition of tumor cell proliferation by sigma ligands is associated with K+channel inhibition and p27kip accumulation.

Clinical trials with sigma ligands.

Beneficial effects of the σ1 receptor agonists igmesine and dehydroepiandrosterone against learning impairments in rats prenatally exposed to cocaine.

Involvement of the sigma1 receptor in the appetitive effects of cocaine.

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