Targeting ligand-operated chaperone sigma-1 receptors in the treatment of neuropsychiatric disorders

Sigma-1 receptors bind cholesterol and remodel lipid rafts in breast cancer cell lines.

Modulation of brainstem opiate analgesia in the rat by σ1 receptor: A microinjection study.

Sigma receptor agonists provide neuroprotection in vitro by preserving bcl-2.

4-IBP, a sigma-1 receptor agonist, decreases the migration of human cancer cells, including glioblastoma cells, in vivo and sensitizes them in vitro to cytotoxic insults of proapoptotic and proautophagic drugs.

Cancer cell cycle modulated by a functional coupling between sigma-1 receptors and Cl-channels.

Steroid pregnenolone sulfate enhances NMDA-receptor-independent long-term potentiation at hippocampal CA1 synapses: Role for L-type calcium channels and sigma receptors.

Interactions between 3,4- methylenedioxymethamphetamine and sigma-1 receptors.

Sigma-1 receptor activation prevents intracellular calcium dysregulation in cortical neurons during in vitro ischemia.

The expression and functional characterization of sigma-1 receptors in breast cancer cell lines.