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  • ABOUT US
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Enhanced kappaopioid receptor-mediated analgesia by antisense targeting the sigma-1 receptor.

PIPELINEBy alessandroJuly 16, 1997

Eur J Pharmacol 331, R5-6, (1997). King, M., Pan, Y. X., Mei, J., Chang, A., Xu, J., & Pasternak, G.W. View abstract in PubMed

SA4503, a novel cognitive enhancer with sigma1receptor agonist properties, facilitates NMDA receptor-dependent learning in mice.

PIPELINEBy alessandroJune 5, 1997

Eur J Pharmacol 328, 9-18, (1997). Maurice, T., & Privat, A. View abstract in PubMed

Neuroprotective and anti-amnesic potentials of sigma (σ) receptor ligands.

PIPELINEBy alessandroJanuary 11, 1997

Prog Neuropsychopharmacol Biol Psychiatry 21, 69-102, (1997) Maurice, T., & Lockhart, B. P. View abstract in PubMed

Interactions of selective serotonin reuptake inhibitors with subtypes of sigma receptors in rat brain.

PIPELINEBy alessandroJune 20, 1996

Eur J Pharmacol 307, 117-119, (1996). Narita, N., Hashimoto, K., Tomitaka, S., & Minabe, Y. View abstract in PubMed

The sigma receptor ligand, reduced haloepridol, induces apoptosis and increases intracellular-free calcium levels [Ca2+]i in colon and mammary adnocarcinoma cell.

PIPELINEBy alessandroFebruary 6, 1996

Biochem Biophys Res Commun 219, 219-226, (1996). Brent, P. J., Pang, G., Little, G., Dosen, P. J., & Van Helden, D. F. View abstract in PubMed

Sigma-1 and sigma-2 receptors are expressed in a wide variety of human and rodent tumor cell lines.

PIPELINEBy alessandroJanuary 15, 1995

Cancer Res 55, 408-413, (1995). Vilner, B. J., John, C. S., & Bowen, W. D. View abstract in PubMed

PRE-084, a sigma selective PCP derivative, attenuates MK-801-induced impairment of learning in mice.

PIPELINEBy alessandroDecember 11, 1994

Pharmacol Biochem Behav 49, 859-869, (1994). Maurice, T., Su, T. P., Parish, D. W., Nabeshima, T., & Privat, A. View abstract in PubMed

Rat liver and kidney contain high densities of sigma-1 and sigma-2 receptors: Characterization by ligand binding and photoaffinity labeling.

PIPELINEBy alessandroJune 15, 1994

Eur J Pharmacol 268, 9-18, (1994). Hellewell, S. B., Bruce, A., Feinstein, G., Orringer, J.,Williams,W., & Bowen,W. D. View abstract in PubMed

Modification of the N-methyl-Daspartate response by antidepressant sigma receptor ligands.

PIPELINEBy alessandroAugust 24, 1993

Pharmacol 240, 319-323, (1993). Bergeron, R., Debonnel, G., & De Montigny, C. View abstract in PubMed

Increase in extracellular acetylcholine level by sigma ligands in rat frontal cortex.

PIPELINEBy alessandroMay 11, 1993

J Pharmacol Exp Ther 265,851-859, (1993) Matsuno, K., Matsunaga, K., Senda, T., & Mita, S. View abstract in PubMed

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