Amyloid-beta junkies

THE LANCET, Vol 355, February 26, 2000 George Perry, Akihiko Nunomura, Arun K Raina, Mark A Smith View Poster

Neuroactive neurosteroids as endogenous effectors for the sigma1 (σ1) receptor: Pharmacological evidence and therapeutic opportunities.

Jpn J Pharmacol 81, 125-155, (1999). Maurice, T., Phan, V. L., Urani, A., Kamei, H., Noda, Y., & Nabeshima, T. View abstract in PubMed

Intracellular σ1 receptor modulates phospholipase C and protein kinase C activities in the brainstem.

Proc Natl Acad Sci USA 96, 8196-8199, (1999). Morin-Surun, M. P., Collin, T., Denavit-Saubie, M., Baulieu, E. E., & Monnet, F. P. View abstract in PubMed

Sigma receptor photolabeling and sigma receptor-mediated modulation of potassium channels in tumor cells.

J Biol Chem 274, 1837-18392, (1999). Wilke, R. A., Mehta, R. P., Lupardus, P. J., Chen, Y., Ruoho, A. E., & Jackson, M. B. View abstract in PubMed

Olfactory bulbectomy increases prepro-enkephalin mRNA levels in the ventral striatum in rats.

Neuropeptides 33, 206-211, (1999). Holmes, P. V. View abstract in PubMed

A-current down-modulated by sigma receptor in frog pituitary melanotrope cells through a G-protein-dependent pathway.

J Pharmacol Exp Ther 289, 321-328, (1999a). Soriani, O., Foll, F. L., Roman, F., Monnet, F. P., Vaudry, H., & Cazin, L. View abstract in PubMed

Binding of dimemorfan to sigma-1 receptor and its anticonvulsant and locomotor effects in mice, compared with dextromethorphan and dextrorphan.

Brain Res 821, 516-519, (1999). Chou, Y. C., Liao, J. F., Chang,W. Y., Lin, M. F., & Chen, C. F. View abstract in PubMed

TAK-147, an acetylcholinesterase inhibitor, increases choline acetyltransferase activity in cultured rat septal cholinergic neurons.

Neurosci Lett 260, 5-8, (1999). Kato, K., Hayako, H., Ishihara, Y., Marui, S., Iwane, M., & Miyamoto, M. View abstract in PubMed

Association between polymorphisms in the type 1 sigma receptor gene and schizophrenia.

Neurosci Lett 257, 45-48, (1998). Ishiguro, H., Ohtsuki, T., Toru, M., Itokawa, M., Aoki, J., Shibuya, H., et al. View abstract in PubMed

Beneficial effects of acute and repeated administrations of sigma receptor agonists on behavioural despair in mice exposed to tail suspension.

Pharmacol Biochem Behav 61, 247-252, (1998). Ukai, M., Maeda, H., Nanya, Y., Kameyama, T., & Matsuno, K. View abstract in PubMed