Amyloid toxicity induced by oligomeric Aβ25-35 injection is enhanced after pharmacologic or genetic invalidation of the σ1 chaperone protein

Endogenous Neuroprotection in Neurodegenerative Diseases, University of Montpellier 2, Inserm U. 710, Montpellier 34095, France. (2013) Tangui Maurice, Fanny Duhr, Alisson Dekeuwer, Nathalie Chevallier. View Poster

Implication of the σ1 chaperone protein in adult neurogenesis: Contribution to neuroprotection?

Endogenous Neuroprotection in Neurodegenerative Diseases, University of Montpellier 2, Inserm U. 710, Montpellier 34095, France. (2013) Nathalie Chevallier, Alisson Dekeuwer, Amandine Falco, Tangui Maurice. View Poster

Targeting ligand-operated chaperone sigma-1 receptors in the treatment of neuropsychiatric disorders

Expert Opin Ther Targets. 2011 May ; 15(5): 557–577. doi:10.1517/14728222.2011.560837. Hayashi Teruo*, Tsai Shang-Yi, Mori Tomohisa, Fujimoto Michiko, and Su Tsung-Ping View Poster

Sigma-1 receptors bind cholesterol and remodel lipid rafts in breast cancer cell lines.

Cancer Res 67, 11166-11175, (2007). Palmer, C. P., Mahen, R., Schnell, E., Djamgoz, M. B., & Aydar, E. View abstract in PubMed

Modulation of brainstem opiate analgesia in the rat by σ1 receptor: A microinjection study.

J Pharmacol Exp Ther 322, 1278-1285, (2007). Mei, J., & Pasternak, G.W. View abstract in PubMed

Sigma receptor agonists provide neuroprotection in vitro by preserving bcl-2.

Anesth Analg 104, 1179-1184, (2007). Yang, S., Bhardwaj, A., Cheng, J., Alkayed, N. J., Hurn, P. D., & Kirsch, J. R. View abstract in PubMed

4-IBP, a sigma-1 receptor agonist, decreases the migration of human cancer cells, including glioblastoma cells, in vivo and sensitizes them in vitro to cytotoxic insults of proapoptotic and proautophagic drugs.

Neoplasia 9, 358-369, (2007). Megalizzi, V., Mathieu, V., Mijatovic, T., Gailly, P., Debeir, O., De Neve, N., et al. View abstract in PubMed

Cancer cell cycle modulated by a functional coupling between sigma-1 receptors and Cl-channels.

J Biol Chem 282, 2259-2267, (2007). Renaudo, A., L’Hoste, S., Guizouarn, H., Borgese, F., & Soriani, O. View abstract in PubMed

Steroid pregnenolone sulfate enhances NMDA-receptor-independent long-term potentiation at hippocampal CA1 synapses: Role for L-type calcium channels and sigma receptors.

Hippocampus 17, 349-369, (2007). Sabeti, J., Nelson, T. E., Purdy, R. H., & Groul, D. L. View abstract in PubMed

Interactions between 3,4- methylenedioxymethamphetamine and sigma-1 receptors.

Eur J Pharmacol 553, 141-145, (2006). Brammer, M. K., Gilmore, D. L., & Matsumoto, R. R. View abstract in PubMed