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  • ABOUT US
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Interactions of selective serotonin reuptake inhibitors with subtypes of sigma receptors in rat brain.

PIPELINEBy alessandroJune 20, 1996

Eur J Pharmacol 307, 117-119, (1996). Narita, N., Hashimoto, K., Tomitaka, S., & Minabe, Y. View abstract in PubMed

The sigma receptor ligand, reduced haloepridol, induces apoptosis and increases intracellular-free calcium levels [Ca2+]i in colon and mammary adnocarcinoma cell.

PIPELINEBy alessandroFebruary 6, 1996

Biochem Biophys Res Commun 219, 219-226, (1996). Brent, P. J., Pang, G., Little, G., Dosen, P. J., & Van Helden, D. F. View abstract in PubMed

Sigma-1 and sigma-2 receptors are expressed in a wide variety of human and rodent tumor cell lines.

PIPELINEBy alessandroJanuary 15, 1995

Cancer Res 55, 408-413, (1995). Vilner, B. J., John, C. S., & Bowen, W. D. View abstract in PubMed

PRE-084, a sigma selective PCP derivative, attenuates MK-801-induced impairment of learning in mice.

PIPELINEBy alessandroDecember 11, 1994

Pharmacol Biochem Behav 49, 859-869, (1994). Maurice, T., Su, T. P., Parish, D. W., Nabeshima, T., & Privat, A. View abstract in PubMed

Rat liver and kidney contain high densities of sigma-1 and sigma-2 receptors: Characterization by ligand binding and photoaffinity labeling.

PIPELINEBy alessandroJune 15, 1994

Eur J Pharmacol 268, 9-18, (1994). Hellewell, S. B., Bruce, A., Feinstein, G., Orringer, J.,Williams,W., & Bowen,W. D. View abstract in PubMed

Loss of sigma binding sites in the CA1 area of the anterior hippocampus in Alzheimer’s disease correlates with CA1 pyramidal cell loss.

Alzheimer's DiseaseBy alessandroOctober 1, 1993

Brain Res 623, 299-302, (1993). Jansen, K. L., Faull, R. L., Storey, P., & Leslie, R. A. View abstract in PubMed

Modification of the N-methyl-Daspartate response by antidepressant sigma receptor ligands.

PIPELINEBy alessandroAugust 24, 1993

Pharmacol 240, 319-323, (1993). Bergeron, R., Debonnel, G., & De Montigny, C. View abstract in PubMed

Increase in extracellular acetylcholine level by sigma ligands in rat frontal cortex.

PIPELINEBy alessandroMay 11, 1993

J Pharmacol Exp Ther 265,851-859, (1993) Matsuno, K., Matsunaga, K., Senda, T., & Mita, S. View abstract in PubMed

Overexpression of sigma receptors in nonneural human tumors.

PIPELINEBy alessandroDecember 15, 1991

Cancer Research 51, 6558-6562, (1991). Wojciech, T. B., Thomas, G. E., Mamone, J. Y., Homan, S. M., Levy, B. K., Johnson, F. R. E., et al. View abstract in PubMed

Evidence for an anti-amnesic effect of JO 1784 in the rat: A potent and selective ligand for the sigma receptor.

PIPELINEBy alessandroApril 19, 1991

Brain Res 546, 282-286, (1991). Earley, B., Burke, M., Leonard, B. E., Gouret, C. J., & Junien, J. L. View abstract in PubMed

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