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  • HOME
  • ABOUT US
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  • INVESTORS
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    • Share Data
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    • Code of Conduct
    • Investor Material
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Predicting the failure of amyloid-beta vaccine

PIPELINEBy alessandroMay 25, 2002

THE LANCET, Vol 359, May 25, 2002 Mark A Smith, Craig S Atwood, James A Joseph, George Perry View Poster

Sigma-2 receptors regulate changes in sphingolipid levels in breast tumor cells.

PIPELINEBy alessandroMay 17, 2002

Eur J Pharmacol 443, 207-209, (2002). Crawford, K.W., Coop, A., & Bowen,W. D. View abstract in PubMed

The sigma receptor as a ligand-regulated auxiliary potassium channel subunit.

PIPELINEBy alessandroApril 25, 2002

Neuron 34, 399-410, (2002). Aydar, E., Palmer, C. P., Klyachko, V. A., & Jackson, M. B. View abstract in PubMed

σ1 Receptor modulation of opioid analgesia in the mouse.

PIPELINEBy alessandroMarch 11, 2002

J Pharmacol Exp Ther 300, 1070-1074, (2002). Mei, J., & Pasternak, G. W. View abstract in PubMed

Effects of sigma ligands on NMDA receptor function in the bulbectomy model of depression: A behavioural study in the rat.

PIPELINEBy alessandroMarch 11, 2002

Int J Neuropsychopharmacol 5, 53-62, (2002). Bermack, J., Lavoie, N., Dryver, E., & Debonnel, G. View abstract in PubMed

Sigma-2 receptor agonists activate a novel apoptotic pathway and potentiate antineoplastic drugs in breast tumor cell line.

PIPELINEBy alessandroJanuary 1, 2002

Cancer Res 62, 313-322, (2002). Crawford, K. W., & Bowen, W. D. View abstract in PubMed

Differential involvement of the sigma-1 receptor in the anti-amnesic effect of neuroactive steroids, as demonstrated using an in vivo antisense strategy in the mouse.

PIPELINEBy alessandroDecember 11, 2001

Br J Pharmacol 134, 1731-1741, (2001). Maurice, T., Phan, V., Urani, A., & Guillemain, I. View abstract in PubMed

Beneficial effect of the sigma-1 receptor agonist PRE-084 against the spatial learning deficits in aged rats.

PIPELINEBy alessandroNovember 16, 2001

Eur J Pharmacol 431, 223-227, (2001) Maurice, T. View abstract in PubMed

The interaction between neuroactive steroids and the sigma1 receptor function: Behavioral consequences and therapeutic opportunities.

PIPELINEBy alessandroNovember 11, 2001

Brain Res Brain Res Rev 37, 116-132, (2001). Maurice, T., Urani, A., Phan, V. L., & Romieu, P. View abstract in PubMed

Expression pattern of sigma receptor 1 mRNA and protein in mammalian retina.

PIPELINEBy alessandroNovember 1, 2001

Brain Res Mol Brain Res 95, 86-95, (2001). Ola, M. S., Moore, P., El-Sherbeny, A., Roon, P., Agarwal, N., Sarthy, V. P., Casellas, P., et al. View abstract in PubMed

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