Neuroprotective effect of sigma-1 receptor ligand 4-phenyl-1-(4-phenylbutyl) piperidine (PPBP) is linked to reduced neuronal nitric oxide production.

Stroke 32, 1613-1620, (2001). Goyagi, T., Goto, S., Bhardwaj, A., Dawson, V. L., Hurn, P. D., & Kirsch, J. R. View abstract in PubMed